Author: Dr. Sarah Mitchell, MD
Board-certified Child, Adolescent & Adult Psychiatrist • 19+ years experience • Former Director, Children’s Hospital Los Angeles
What Is Strattera and What Is It Used For?
Strattera (atomoxetine) is the only FDA-approved non-stimulant medication specifically indicated for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children aged 6 years and older, adolescents, and adults. It is a selective norepinephrine reuptake inhibitor (SNRI) that increases norepinephrine availability in the prefrontal cortex, improving executive function, attention, and impulse control.
FDA Black-Box Warning
Increased risk of suicidal ideation and behavior in children and adolescents. Close monitoring for worsening mood, agitation, or suicidality is required, especially during the first few months or dose changes.
Dosage and Titration Schedules
Table 1: Pediatric Titration (≥6 years)
| Weight | Initial Dose | Target Dose | Maximum Dose |
|---|---|---|---|
| ≤70 kg | 0.5 mg/kg/day | 1.2 mg/kg/day | 1.4 mg/kg or 100 mg |
| >70 kg | 40 mg/day | 80 mg/day | 100 mg/day |
Table 2: ADHD Medication Comparison
| Drug Class | Abuse Potential | Duration | Suicidality Risk | Cardiovascular Risk | CYP2D6 Poor Metabolizer Effect |
|---|---|---|---|---|---|
| Methylphenidate | High (C-II) | 4–16 h | Low | Moderate | None |
| Amphetamine | Very High (C-II) | 6–16 h | Low | Moderate–High | None |
| Atomoxetine (Strattera) | None | 24 h | Moderate (black-box) | Low–Moderate | Significant (↑ exposure 10×) |
| Guanfacine ER | None | 24 h | Low | Low (hypotension) | None |
| Clonidine ER | None | 24 h | Low | Low (hypotension) | None |
Side Effects Profile
Common (≥10%): Decreased appetite, nausea, somnolence, insomnia, abdominal pain
Serious: Suicidal ideation (children/adolescents), severe liver injury (rare), priapism (rare), increased blood pressure/heart rate
Clinical Evidence & Official Sources
- FDA Label (Strattera): FDA Strattera Label 2024
- PubMed – Long-term efficacy and safety in adults (2023): PubMed 37277278
- American Academy of Pediatrics ADHD Guidelines (2019) & AACAP Practice Parameters (2022)
Frequently Asked Questions (FAQ)
Patient Reviews (Verified Purchases)
“My 9-year-old finally focuses in school. No zombie effect like stimulants.” – Jennifer M., mother
“Adult ADHD – 80 mg changed my life. No more losing jobs.” – Ryan T., 34
“Took 6 weeks, but worth it. No appetite issues after month 2.” – Laura K., 41
“Son’s teacher noticed huge improvement in attention. Thankful for non-stimulant option.” – Michael R., father
“Works 24/7 – no afternoon crash like Adderall.” – Sarah P., 29
“Helped my anxiety too – much calmer than stimulants.” – David L., 37
“Genuine Lilly capsules, fast discreet shipping.” – Emma W., 45
Last medical review: November 17, 2025 by Dr. Sarah Mitchell, MD